Education: Ph.D., Georgia State University, Center for Behavioral Neuroscience (2002)
Postdoctoral Training: The Rockefeller University
Emory University School of Medicine
Graduate Areas: Experimental - Behavioral Neuroscience
Specialty: Behavioral Neuroscience/Molecular Biology/Neurophysiology
The Jasnow lab focuses on discovering how environmental experience alters emotional learning, as well as the molecular and cellular mechanisms of fear learning. PTSD and other fear-related disorders are thought to result from an interaction of genetic and environmental factors that enhance the likelihood of a pathological stress response and fear memory following severe trauma. Thus, if we can understand how genetic factors and environmental experience interact to alter basic brain function and ultimately emotional behavior, we can understand how these psychiatric disorders arise and develop potential therapeutic interventions. We use virus-mediated genetic manipulation and transgenic mouse models to discover the basic underlying brain mechanisms regulating prolonged physiological and behavioral responses to traumatic experience.
Lab Site: Behavioral Neuroscience Laboratory
Courses Frequently Taught
- Biopsychology (undergraduate)
- Neural Mechanisms of Learning and Memory (undergraduate/graduate)
- Current Techniques in Behavioral Neuroscience (undergraduate/graduate)
Scholarly, Creative & Professional Activities
*Lynch, J. L. III, *Dejanovis, D., *Winiecki, P., *Mulvany, J., *Ortiz, S., Riccio, D. C., & Jasnow, A. M. (2014). Activation of ERβ modulates fear generalization through and effect on fear memory retrieval. Hormones and Behaviors, 66: 421-429.
*Cullen, P. C., *Dulka, B. N., *Ortiz, S., Riccio, D. C., & Jasnow, A. M. (2014). GABA-mediated presynaptic inhibition is required for precision of long-term memory. Learning and Memory, 21(4): 180-184.
*Meduri, J. M., Farnbauch, L. A., & Jasnow, A. M. (2013). Paradoxical enhancement of fear expression and extinction deficits in mice resilient to social defeat. Behavioral Brain Research, 256C: 580-590.
*Lynch, J. L. III., *Cullen P. C., Jasnow, A. M., & Riccio, D. C. (2013). Sex differences in the generalization of fear as a function of retention intervals. Learning and Memory, 20: 628-632.
Jasnow, A. M., Ehrlich, D. E., Choi, D. C., Dabrowska, J., Bowers, M. E., McCullough, K. M., Rainnie, D. G., & Ressler, K. J. (2013). Thy1-expressing neurons in the basolateral amygdala may mediate fear inhibition. The Journal of Neuroscience, 33(25): 10396-404.
Jasnow, A. M., Cullen, P. C., & Riccio, D. C. (2012). Remembering another dimension of forgetting. Frontiers in Psychology, 3:1-8.
Ryan, S. J., Ehrlich, D. E., Jasnow, A. M., Daftary, S., Madsen, T. E., & Rainnie, D. G. (2012). Spike-timing preceision and neuronal synchrony are enhanced by an interaction between sunaptic inhibition and memrane oscillations in the amygdala. PLoS One, 7: e35320.
Gerecke, K. M., Kishore, R., Jasnow, A. M., Quadros-Menella, P., Parker, S., Kozub, F. J., Lambert, K. G., & Kinsley, C. H. (2012). Alterations of sex-typical microanatomy: prenatal stress modifies the structure of medial preoptic area neurons in rats. Developmental Psychobiology, 54(1): 16-27.
Jasnow, A. M., Ressler, K. J., Hammack, S. E., Chhatwal, J. P., & Rainnie, D. G. (2009). Distinct subtypes of Cholecystokinin-containing interneurons of the basolateral amygdala identified using a CCK promoter-specific lentivirus. Journal of Neurophysiology, 101: 1494-1506.
Jasnow, A. M., Mong, J. A., Romeo, R. D., & Pfaff, D. W. (2007). Estrogenic regulation of gene and protein expression within amygdala of female mice. Endocrine, 32: 271-279.
- Behavioral Neuroscience
- Fear and anxiety, Emotion
- Molecular biology